Immunohistochemistry of Ecchordosis Physaliphora and Chordoma

Multiple Ecchordosis Physaliphora: A Challenging Diagnosis

Ecchordosis physaliphora (EP) is a benign congenital hamartoma of the ectopic notochordal remnant, accounting for 0.5–2% of all autopsies, and found in 1.5% of all magnetic resonance imaging (MRI) of the brain. It commonly occurs along the midline within the retroclival and the prepontine cistern. EP has a slow growth rate and can vary in size from a few mm to 2 cm.[1] Giant symptomatic EPs are...

Retroclival ecchordosis physaliphora: MR imaging and review of the literature.

BACKGROUND AND PURPOSE Ecchordosis physaliphora (EP), found in about 2% of autopsies, is a clinically inconspicuous notochordal remnant appearing at the dorsal wall of the clivus. To our knowledge, a systematic review of its MR features does not exist. The aim of this study was to describe the MR imaging findings of incidentally found retroclival EP with special respect to its differentiation f...

A Unique Case Of Ecchordosis Physaliphora With Intratumoral Haemorrhage

Ecchordosis physaliphora is a small, gelatinous tissue that is considered an ectopic notochordal remnant. This tissue is located in the midline of the craniospinal axis, reaching from the dorsum sellae to the sacrococcygeal region (1-4). Intracranial EP is typically found intradurally in the pre-pontine cistern, where it is attached to the dorsal wall of clivus via a small pedicle (1, 2, 5). Ec...

A case of ecchordosis physaliphora presenting with an intratumoral hemorrhage.

Ecchordosis physaliphora is a rare congenital, benign, hamartomatous, retroclival mass derived from notochordal tissue that is typically located intradurally in the prepontine cistern. Ecchordosis physaliphora is usually asymptomatic. In rare cases, ecchordosis physaliphora can be symptomatic due to tumor expansion and compression of the surrounding structures and extratumoral hemorrhage. To ou...

Notochord Pathology in the cranio-cervical junction: chordomas. Ecchordosis Physaliphora vs chordomas with low radiological agressivity: a diagnostic challenge